Research group of chronic inflammatory oral diseases and systemic diseases associated with oral health

INTRODUCTION

This active research group was purposefully formed to solve oral health problems of people in the northeast of Thailand and the Greater Mekong Subregion (GMS).

This research group aims at;

  • Producing high-quality research articles published in peer-reviewed journals, both domestically and internationally.
  • Strengthening research capacity in novice researchers to take part in the establishment of a research center for chronic inflammatory oral diseases in the near future.
  • Building a strong research network of oral diseases and systemic diseases associated with oral health such as cardiovascular diseases, hematologic diseases, infectious diseases and diabetes mellitus by enhancing research knowledge sharing and collaboration, from interfaculty to international levels.
  • Promoting the application of research knowledge into diagnostic processes, treatment planning and follow-up care in patients with chronic inflammatory oral diseases.
  • Conveying new knowledge gained from research to both public and private sectors for linking production and service lines to take an integral part in research and development to help solve oral health problems of the people.

CURRENT RESEARCH PROJECT / RESEARCH INTEREST

  • Systemic health vs oral health
  • Periodontal diseases
  • Pathogenesis of chronic inflammatory oral diseases, potentially malignant disorders, and oral cancer
  • Innovations and novel treatments for chronic inflammatory oral diseases, potentially malignant disorders, and oral cancer
  • Development of oral cancer spheroids to use as a model for oral cancer treatment

SELECTED PUBLICATION

  1. Hormdee D, Rinsathorn W, Puasiri S, Jitprasertwong P. Anti-early stage of bacterial recolonization effect of curcuma longa extract as photodynamic adjunctive treatment. Int J Dent. 2020:8823708. doi: 10.1155/2020/8823708.
  2. Hormdee D, Yamsuk T, Sutthiprapaporn P. Palatal soft tissue thickness on maxillary posterior teeth and its relation to palatal vault angle measured by cone-beam computed tomography. Int J Dent. 2020:8844236. doi: 10.1155/2020/8844236.
  3. Kantrong N, Jit-Armart P, Arayatrakoollikit U. Melatonin antagonizes lipopolysaccharide-induced pulpal fibroblast responses. BMC Oral Health. 2020;20(1):91. doi: 10.1186/s12903-020-1055-3.
  4. Chanomethaporn A, Chayasadom A, Wara-Aswapati N, Kongwattanakul K, Suwannarong W, Tangwanichgapong K, Sumanonta G, Matangkasombut O, Dasanayake AP, Pitiphat W. Association between periodontitis and spontaneous abortion: A case-control study. J Periodontol. 2019;90(4):381-390. doi: 10.1002/JPER.18-0174.
  5. Hormdee D, Prajaneh S, Kampichai A, Tak R, Chaiyarit P. Prolonged suppressive effects of periodontitis on salivary TFF3 production. Eur J Dent. 2019;13(2):193-198. doi: 10.1055/s-0039-1693949.
  6. Dien VHA, McKinney CM, Pisek A, Pitiphat W. Maternal exposures and risk of oral clefts in South Vietnam. Birth Defects Res. 2018;110(6):527-537. doi: 10.1002/bdr2.1192.
  7. Thi Do T, Phoomak C, Champattanachai V, Silsirivanit A, Chaiyarit P. New evidence of connections between increased O-GlcNAcylation and inflammasome in the oral mucosa of patients with oral lichen planus. Clin Exp Immunol. 2018;192(1):129-137. doi: 10.1111/cei.13091.
  8. Chaiyarit P, Luengtrakoon K, Wannakasemsuk W, Vichitrananda V, Klanrit P, Hormdee D, Noisombut R. Biological functions of melatonin in relation to pathogenesis of oral lichen planus. Med Hypotheses. 2017; 104: 40-44. doi: 10.1016/j.mehy.2017.05.021.
  9. Luengtrakoon K, Wannakasemsuk W, Vichitrananda V, Klanrit P, Hormdee D, Noisombut R, Chaiyarit P. Increased melatonin in oral mucosal tissue of oral lichen planus (OLP) patients: A possible link between melatonin and its role in oral mucosal inflammation. Arch Oral Biol. 2017;78:13-19. doi: 10.1016/j.archoralbio.2017.02.007.

CONTACT ADDRESS

Research Group of Chronic Inflammatory Oral Diseases and Systemic Diseases Associated with Oral Health, Faculty of Dentistry, Khon Kaen University
123 Mitraphab Road, Muang, Khon Kaen, 40002, Thailand.
Tel: (043) 202405 Ext. 45123 Fax: (043) 202862
E-mail: porakla@kku.ac.th